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Guillain-Barre Syndrome



Guilian-Barre Syndrome ICD-9

  • 357.0 Acute infective polyneuritis  Guillain-Barre  syndrome

Guillain-Barre Syndrome Etiology / Epidemiology / Natural History

  • Immune-mediated segmetal peripheral nerve demyelination.

Guillain-Barre Syndrome Anatomy

Guillain-Barre Syndrome Clinical Evaluation

  • Loss of deep tendon reflexes, vague numbness and tingling, progressive weakness disporportionate to sensory loss.
  • May have back pain.
  • Symptoms often preceeded by upper respiratory illness, or GI infection.
  • Weakness progresses over hours to days, reaching its maximum after several weaks.
  • May progress to complete paralysis.

Guillain-Barre Syndrome Xray / Diagnositc Tests

  • EMG/NCV: demonstrates conduciton slowing and conduction block. Sural sparing on EMG/NCV.
  • Elevated spinal fluid protein without pleocytosis.

Guillain-Barre Syndrome Classification / Treatment

  • Hospitalization for monitoring, may require ventilatory support.
  • Plasmapheresis, intravenous immunoglobulin therapy shorten the duration of illess (Lancet 1997;349:225).

Guillain-Barre Syndrome Associated Injuries / Differential Diagnosis

Guillain-Barre Syndrome Complications

  • Mortality generally from respiratory compromise.

Guillain-Barre Syndrome Follow-up Care

  • Referral to internist for medical management.

Guillain-Barre Syndrome Review References

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